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. 2006 Aug;15(4):280–285. doi: 10.1136/tc.2005.015487

Table 2 Effect of NRT on long‐term smoking cessation.

Study NRT Placebo Weight (%) OR (95% CI)
Blondal 1989 29/92* (30)† 21/90 (22) 9.9 1.51 (0.78 to 2.92)
Blondal 1997 15/79 (20) 11/78 (13) 7.3 1.43 (0.61 to 3.34)
Blondal 1999 19/118 (32) 10/119 (13) 7.7 2.09 (0.93 to 4.72)
Clavel 1997 30/481 (53) 32/515 (43) 12.5 1.00 (0.60 to 1.68)
Daughton 1999 39/193 (50) 15/202 (19) 10.3 3.16 (1.68 to 5.94)
Glavas 2003 10/56 (13) 8/56 (9) 5.7 1.30 (0.47 to 3.60)
Herrera 1995 30/76 (37) 13/78 (17) 8.5 3.26 (1.54 to 6.92)
Mikkelsen 1994 15/145 (24) 4/144 (6) 4.8 4.04 (1.31 to 12.5)
Richmond 1997 21/153 (29) 8/152 (14) 7.3 2.86 (1.23 to 6.69)
Stapleton 1998 19/116 (33) 7/111 (14) 6.7 2.91 (1.17 to 7.23)
Tonnesen 1988 17/60 (23) 5/53 (12) 5.2 3.80 (1.29 to 11.2)
Yudkin 2003 48/815 (91) 35/810 (62) 14.0 1.39 (0.89 to 2.17)
Total 292/2384 (435) 169/2408 (244) 100 1.99 (1.50 to 2.64)

Random effects test of overall effect: Z = 4.79, p<0.001.

*Number of participants who successfully maintained smoking cessation/number entering trial.

†Figures in brackets give number successful at earlier 12 month follow up.

CI, confidence interval; OR, odds ratio.