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. 2006 Oct;15(5):373–376. doi: 10.1136/tc.2005.014514

Table 2 Results of randomised controlled trial of nicotine versus placebo patches.

Randomised to active treatment Randomised to placebo treatment
Total numbers 49 49
Mean age in years 14.9 14.7
Percentage female 64 56
Median exhaled CO (ppm) 12.9 11.8
CO validated point abstinence at 4 weeks 5 4
CO validated point abstinence at 13 weeks 0 0
Completed full six week treatment course 3 5
Withdrew because of adverse event 1 1
Other non‐severe adverse events*
 Itching 16 7
 Rash 6 3
 Pain or paraesthesia at patch site 6 4
 Dizziness, nausea or headache 2 3

*Some participants experienced more than one adverse effect.

CO, carbon monoxide.