Table 1. Parameters used in simulation of glutamate diffusion.

Parameter	Value	Notes	References
Temperature	33°C
Q 10 (diffusion)	1.4/10°C
Q 10 (rate constants)	2.2/10°C		[110]
Diffusion coefficient	5.0 cm2/s	7.6 cm2/s in free solution	[106]
Cleft width	15 nm		[38]
Synapse area	0.12 µm2		[43]
Glutamate in vesicle	2000	200 mM	[119]
Transporter membrane fraction	0.1	10000/µm2	[111]
Transporter binding rate	3.2×107/M·sec		[112]
Transporter unbinding rate	3016/sec		[112]
Transporter transport rate	905/sec		[112]