Skip to main content
. Author manuscript; available in PMC: 2009 Oct 3.
Published in final edited form as: J Mol Biol. 2008 Jul 22;382(2):448–457. doi: 10.1016/j.jmb.2008.07.037

Figure 6. Thiol-disulfide exchange reactions of 6H-Ibα-TM and Ibβ-TM in 5.0 mM DM without (top panel) or with (bottom) IX-TM.

Figure 6

The reactions as well as the assignment of HPLC peaks followed the description in the legend of Figure 4. Peak 12: 6H-αβ2, or (Ibβ-TM)-SS-(6H-Ibα-TM)-SS-(Ibβ-TM); 13: (6H-Ibα-TM)-SS-(Ibβ-TM); 14: oxidized 6H-Ibα-TM with an intramolecular disulfide; 15: 6H-Ibα-TM; 16: (Ibβ-TM)-SS-(6H-Ibα-TM)-SS-(6H-Ibα-TM)-SS-(Ibβ-TM). The dotted line highlights the difference in 6H-αβ2 production between the two reactions.