Table 2.
Unadjusted and multivariable-adjusted associations of coronary heart disease (CHD) risk factors, inflammatory factors with presence of coronary artery calcium and more extensive coronary artery calcium in women with systemic lupus erythematosus or rheumatoid arthritis compared to age- and race-matched controls
Outcome variables* | Unadjusted OR
(95% CI) |
CHD risk factors
Adjusted OR (95% CI) |
CHD risk factors and inflammatory factors
Adjusted OR (95% CI) |
---|---|---|---|
Presence of CAC | 1.87 (1.09-3.21) | 2.16 (1.15-4.06) | 1.53 (0.74-3.14) |
More extensive CAC | |||
1-10 | 1.69 (0.85-3.35) | 2.15 (0.99-4.67) | 1.45 (0.60-3.54) |
11-100 | 1.44 (0.68-3.07) | 1.69 (0.72-3.95) | 1.19 (0.46-3.11) |
>100 | 4.04 (1.42-11.56) | 3.83 (1.23-11.89) | 2.89 (0.85-9.89) |
CAC=coronary artery calcium; CHD risk factors: history of smoking, postmenopausal status, hypertension, HOMA-IR (log) and total cholesterol/high density lipoprotein cholesterol ratio, homocysteine; inflammatory features: hsC-reactive protein (log), sICAM-1 (log); OR=odds ratio. 95% CI=95% confidence interval