Table 2 Performance of the Clearview with PCR test in detection of C trachomatis infection by recruitment setting and specimen type†.
| Source and type of specimens | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|
| (95% CI) | (95% CI) | (95% CI) | (95% CI) | |
| FRC (n = 587) | ||||
| Vaginal swab | 24.2* (14.9 to 36.6) | 99.4 (98.2 to 99.9) | 84.2 (59.5 to 95.8) | 91.2 (88.5 to 93.3) |
| Cervical swab | 44.4 (32.1 to 57.4) | 99.4 (98.2 to 99.9) | 90.3 (73.1 to 97.5) | 93.7 (91.3 to 95.5) |
| STDC (n = 839) | ||||
| Vaginal swab | 36.8* (28.2 to 46.2) | 98.9 (97.7 to 99.5) | 84.3 (70.9 to 92.5) | 90.6 (88.3 to 92.5) |
| Cervical swab | 52.6 (43.1 to 61.9) | 96.7 (95.0 to 97.8) | 71.8 (60.8 to 80.7) | 92.7 (90.6 to 94.4) |
| SEV (n = 71) | ||||
| Vaginal swab | 38.9 (18.3 to 63.9) | 100.0 (91.6 to 100) | 100.0 (56.1 to 100) | 82.8 (70.9 to 90.7) |
| Cervical swab | 50.0 (26.8 to 73.2) | 100.0 (91.6 to 100) | 100.0 (62.9 to 100) | 85.5 (73.7 to 92.7) |
| Total (n = 1497) | ||||
| Vaginal swab | 32.8** (26.5 to 39.9) | 99.2 (98.4 to 99.6) | 85.7 (75.5 to 92.3) | 90.5* (88.8 to 91.9) |
| Cervical swab | 49.7 (42.6 to 56.9) | 97.9 (96.9 to 98.6) | 78.4 (70.0 to 85.1) | 92.8 (91.3 to 94.1) |
*p<0.05 and **p<0.01, the p values (χ2 test) refer to the differences between different swab specimens in terms of recruitment settings.
†Performance as compared to PCR test using the corresponding specimens.
CI, confidence interval; FRC, female re‐education centre; NPV, negative predictive value; PCR, polymerase chain reaction; PPV, positive predictive value; STDC, sexually transmitted diseases clinic; SEV, sex entertainment venue.