Skip to main content
. 2006 Jul;43(7):e38. doi: 10.1136/jmg.2005.037507

Table 231P‐MRS data from occipital lobes and calf muscle of the proband (case IV‐4) harbouring the 13042G→A/ND5 mtDNA mutation.

Occipital lobes Calf muscle
[PCr] (mM) [Pi] (mM) [ADP] (μM) PP (mM−1) PCr (mM) rest Pi (mM) rest Post‐exercise TC PCr (s)
Case (IV‐4) 3.79* 1.69* 37* 49* 27.2 4.16 55*
Control
 (mean (SD)) 4.57 (0.19) 1.36 (0.13) 27 (2) 81 (5) 27.9 (1.12) 4.02 (0.56) 19 (4)
 (range) (4.16 to 4.78) (1.11 to 1.50) (24 to 32) (74 to 90) (25.5 to 29.2) (3.12 to 4.80) (11 to 27)

*Outside the normal range.

MRS, magnetic resonance spectroscopy; PCr, phosphocreatine; Pi, inorganic phosphate; PP, phosphorylation potential ( = [ATP]/[ADP]×[Pi]); TC PCr, time constant of phosphocreatine resynthesis rate after exercise.

HHS Vulnerability Disclosure