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. 2008 Oct 9;118(11):3598–3608. doi: 10.1172/JCI36277

Figure 2. Reduced body weight and fast-twitch muscle mass in Myoz1-deficient mice.

Figure 2

(A) Significant reduction in body weight of Myoz1 KO mice (n = 13–15) and (B) in body weight normalized to tibia length in Myoz1 KO mice (n = 6). (C) Morphology of skinned hindlimbs of Myoz1 KO mouse, revealing a slimmer shape of the calf in Myoz1 KO mice compared with WT littermate. Original magnification, ×4. (D) Weight of gastrocnemius in Myoz1 KO mice compared with WT littermates (n = 13–15). (E) Gastrocnemius mass normalized to tibia length (n = 6). (F) Weight of soleus in Myoz1 KO mice compared with WT controls. (G) Soleus weight normalized to tibia length. *P < 0.05, P < 0.01, P < 0.001.

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