Table 4 Variants of uncertain significance.

Pat‐ ient ID	Race	BRCA1 or 2	Variant	Classification
1	White	BRCA2	K3326X	PROB_POLY
2	White	BRCA2	C197C and K3326X	PROB_POLY
3	White	BRCA2	Y42C and I505T	UNLIKELY
4	White	BRCA2	V2728I	UNLIKELY
5	White	BRCA1	R1347G	PROB_POLY
6	White	BRCA2	P655R	UNCERTAIN
7	White	BRCA2	A2951T	PROB_POLY
8	White	BRCA1	R1203Q	UNCERTAIN
9	White	BRCA2	K3392T	PROB_POLY
10	White	BRCA2	M1137T and S2247G	UNLIKELY
11	White	BRCA1	R1347G	PROB_POLY
12	White	BRCA1	Q804H	UNCERTAIN
13	AA	BRCA2	A2466V	PROB_POLY
14	White	BRCA2	K3326X	UNLIKELY
15	AA	BRCA2	Q2384K V3079I	UNCERTAIN
16	AA	BRCA2	D1420Y	UNLIKELY
17	White	BRCA2	A1170V	UNCERTAIN
18	AA	BRCA2	A248T	UNCERTAIN
19	White	BRCA1	R1347G	PROB_POLY
20	White	BRCA1	R496H	PROB_POLY
21	White	BRCA1	R1347G	PROB_POLY
22	White	BRCA2	G1529R	UNCERTAIN
23	AA	BRCA2	A2446V	UNLIKELY
24	White	BRCA1	Q1452G	UNCERTAIN
25	AA	BRCA1	T779Ala	UNCERTAIN
26	AA	BRCA2	I1364L and H2116R	UNLIKELY
27	AA	BRCA1	T37R	UNCERTAIN
28	AA	BRCA2	Q713L	UNLIKELY
29	AA	BRCA2	D935N	UNCERTAIN
30	AA	BRCA2	G3212R and Q713L	UNLIKELY
31	AA	BRCA2	Lys1765Asn	UNLIKELY
32	AA	BRCA2	Q2384K and V30791	UNLIKELY
33	AA	BRCA1	T790A	UNCERTAIN
34	White	BRCA2	IVS20‐16C>G	UNCERTAIN
35	White	BRCA2	L1356L	PROB_POLY

AA, African American; PROB_POLY, based on available data, these variants are likely to be polymorphisms; UNLIKELY, based on available data, these variants are unlikely to be associated with disease risk (see Discussion); UNCERTAIN, based on available data, the significance of these variants remains uncertain.