Figure 2. Mean improvements from baseline adjusted for baseline values Australian/Canadian Osteoarthritis Hand Index (AUSCAN) pain (A), AUSCAN stiffness (B), AUSCAN physical (C), pain visual analogue scale (VAS) (D) and global VAS (E) in patients receiving CRx-102 and placebo (intention to treat population) with one-sided p values for the differences of adjusted least square means.