. Author manuscript; available in PMC: 2008 Nov 1.

Published in final edited form as: Neurochem Res. 2008 May 7;33(11):2229–2240. doi: 10.1007/s11064-008-9700-2

Table 3.

Effect of NMDA on brain PGE₂ and TXB₂ concentrations in chronic vehicle- and valproate-treated rats

	Chronic vehicle		Chronic valproate		Valproate × NMDA interaction
	Saline	NMDA	Saline	NMDA	P-value
PGE₂ (ng/g brain)	7.6 ± 1.5	16.4 ± 4.4^**	2.6 ± 0.4^***	2.8 ± 0.7	0.003
TXB₂ (pg/g brain)	41.4 ± 2.8	88.5 ± 8.9^***	22.8 ± 3.7^***	23.1 ± 0.7	< 0.001

Each value is a mean ± SD (n = 4).

^**

P < 0.01,

^***

P < 0.001; vehicle plus NMDA versus vehicle plus saline, valproate plus saline versus vehicle plus saline, valproate plus NMDA versus valproate plus saline