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Effect of XK-Ras2AG12V and progesterone on Na+ pump currents. The ouabain-inhibitable currents were measured by the two-electrode voltage-clamp technique at a membrane potential of −50 mV. Oocytes expressing XENaCF + XK-Ras2AG12V or XENaCF in the presence of 15 μM progesterone showed no Na+ pump activity in contrast to control oocytes expressing XENaCF.
