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. Author manuscript; available in PMC: 2008 Oct 8.
Published in final edited form as: Expert Rev Dermatol. 2007;2(4):451–469. doi: 10.1586/17469872.2.4.451

FIGURE 3. Lentigo maligna melanoma arising on sun damaged skin.

FIGURE 3

A–B. A typical lentigo maligna melanoma (LMM- invasive melanoma, dark central region) arising in long standing patch of lentigo maligna (melanoma in situ, large irregular brown patch) occurring in sun damaged skin of an elderly female. C. Early vertical growth phase LMM characterized by small nest of melanoma within the papillary dermis found in association with confluent nests of LM found along the dermal-epidermal junction. D. Antibodies to CD117/c-kit demonstrate strong and intense expression of the both in situ and invasive components.