Table 2. Effects of vaccination on H pylori infection (second study).

	Volunteer
Vaccine Ty21a control
	8	13	18	23			29			71			77		81		90			96		98			101			102			103			104		108		121	125			127			129						132
Test*
H pylori culture	+	+	–	–			+			+			+		+		–			+		+			+			+			+			–		+		–	+			+			–						+
RUT	+	+	–	+			+			+			–		+		–			–		+			+			+			+			–		–		+	+			+			+						–
UBT	+	+	–	+			+			+			+		+		–			+		+			+			+			+			–		+		+	+			+			+						–
H pylori histology	+	+	+	+			+			+			+		+		+			+		+			+			+			+			–		+		+	+			+			+						–
Score	4	4	1	3			4			4			3		4		1			3		4			4			4			4			0		3		3	4			4			3						1
Vaccine Ty21a(pUreA/B)
Volunteer						5			12		16			39		48			70				72			78			87			99		106		119
Test
H pylori culture						+			+		+			+		+			+				–			+			+			+		+		+
RUT						+			+		–			+		–			+				–			+			+			–		+		+
UBT						+			+		–			+		–			+				–			+			+			+		+		+
H pylori histology						+			+		–			+		+			+				+			+			+			+		–		+
Score						4			4		1			4		2			4				1			4			4			3		3		4
Vaccine Ty21a(pHP0231)
Volunteer					14			19				35			43			46			60			66			73			75			91		107		117
Test
H pylori culture					+			+				+			+			+			+			+			+			+			+		–		+
RUT					+			+				+			+			+			+			+			+			+			+		–		+
UBT					+			+				+			+			+			+			+			+			+			+		–		+
H pylori histology					+			+				+			+			+			+			+			+			+			+		–		+
Score					4			4				4			4			4			4			4			4			4			4		0		4

*For definition of tests and score see the footnotes of table 1.

RUT, rapid urease test; UBT, [13C]urea breath test.