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Study Parameters at Baseline
| Doxycycline n=20 |
Placebo n=24 |
|
|---|---|---|
| Aortic Diameters (mm) | ||
| Maximum | 57.2±2.1 | 57.2±2.4 |
| At Lowest Renal Artery | 22.5±0.6 | 23.4±0.5 |
| 5mm inferior | 22.5±0.9 | 23.6±0.7 |
| 10mm inferior | 24.1±0.7 | 23.4±0.6 |
| 15mm inferior | 24.6±0.7 | 24.0±0.7 |
| Circulating Markers (pg/ml) | ||
| MMP-9 | 45380±15238 | 57860±13910 |
| MMP-2 | 199570±36919 | 211492±33702 |
| IL-6 | 3.8±3.1 | 6.6±2.9 |
| IL-8 | 1.9±1.1 | 3.0±1.0 |
| CRP | 56.0±13.3 | 47.5±12.2 |
