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. 2008 Jan 3;45(5):275–283. doi: 10.1136/jmg.2007.055277

Table 3. LOD scores >1.5 and p values of multipoint linkage analysis for muscle and bone cross-sectional area (MBA) and knee strength phenotypes .

Trait SNP Location cM LOD unadjusted pValue Empirical p value LOD covariate MBA LOD covariate MBA + Sport index
>1.5 LOD regions for unadjusted phenotypes (and comparison after covariation)
MBA mid thigh rs695167 8q13.2 79.78 1.719 0.002 0.016 1.254*
rs296736 12q13.13 63.82 1.783 0.002 0.012 1.712*
rs926949 14q32.2 109.13 2.998 0.0001 0.0049 2.854*
rs7175643 15q32.2 99.82 2.048 0.0011 0.0102 1.078*
Torque at 30° flexion rs1445128 2p24.2 41.12 2.572 0.0003 0.0097 1.532 1.615
rs246079 12q24.11 124.26 1.791 0.002 0.018 0.335 0.463
Torque–length flexion rs7846911 9q21.32 81.01 2.004 0.0012 0.0003 2.858 2.824
rs4962424 10q26.13 153.12 1.81 0.002 0.003 2.524 2.524
rs225553 12q24.32 147.91 1.615 0.003 <0.001 1.261 1.259
rs760267 14q24.3 76.68 4.088 0.00001 <0.00001 2.972 2.895
Torque–length extension rs13320 1q21.3 145.69 2.326 0.0005 <0.0001 2.064 2.032
rs714513 2p23.3 50.2 2.690 0.0002 <0.0001 2.654 2.627
rs9328112 6p25.2 7.27 2.079 0.001 <0.001 2.009 2.004
rs1998825 10q26.3 166.36 1.877 0.002 <0.001 1.733 1.725
rs169631 12q24.31 141.2 1.751 0.002 <0.001 1.308 1.291
rs3785513 17q25.3 137.3 1.746 0.002 <0.001 1.644 1.669
rs1010800 18q11.2 43.66 2.205 0.0007 <0.0001 2.173 2.175
Additional >1.5 LOD regions after adjustment for covariates
MBA mid thigh rs1880542 2q14.2 130.66 1.438 1.592*
Torque at 30° flexion rs2056865 7q31.2 122.77 1.140 1.522 1.516
rs8035183 15q23 74.51 0.262 1.853 1.777
Torque at 60° extension rs1556611 10q23.31 109.44 0.117 1.566 1.695
rs1941487 18p11.31 21.53 0.383 2.394 2.321

MBA, muscle and bone cross-sectional area of the mid thigh.

*Sport Index.