Table V.
WHAP haplotype analyses Omnibus Test for Association in Caucasian and Hispanic Sub-Groups
| Caucasian sample
N=386 young adults |
Hispanic Sample
N=104 young adults |
|||
|---|---|---|---|---|
| Haplotype | Frequency | β | Frequency | β |
| TATC | 0.331 | 0.000 | 0.488 | 0.000 |
|
| ||||
| GGCC | 0.236 | -0.384 | 0.176 | -0.116 |
|
| ||||
| TATT | 0.130 | -0.139 | 0.096 | 1.137 |
|
| ||||
| TACC | 0.078 | 0.449 | 0.077 | 0.152 |
|
| ||||
| TACT | 0.095 | -0.162 | 0.041 | 0.610 |
|
| ||||
| GGCT | 0.064 | -0.127 | 0.020 | -0.048 |
|
| ||||
| TGCC | 0.046 | 0.106 | 0.033 | 0.874 |
|
| ||||
| GACC | 0.020 | 1.001 | 0.057 | 0.409 |
|
| ||||
| GATC | n.o. | n.o. | 0.012 | -0.259 |
|
| ||||
| LRT | 11.239 | 5.268 | ||
| p | 0.129 | 0.729 | ||
| Empirical p | 0.179 | 0.778 | ||
Note. Frequency column shows the frequency of each estimated haplotype in the sample. β column provides the β coefficient estimate derived from the logistic regression test for association. LRT – Likelihood Ratio Test, p – statistical significance, Empirical p-determined after permutation testing. N.o. – not observed.