Skip to main content
. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Eur J Cell Biol. 2008 Jun 24;87(8-9):743–750. doi: 10.1016/j.ejcb.2008.03.011

Fig. 2.

Fig. 2

(Upper panel) Scheme of biofunctionalised nanopatterns to control integrin clustering (Arnold et al., 2004): gold dots are functionalised by c(-RGDfK-) thiols; glass areas between cell-adhesive gold dots are covalently bound to polyethyleneglycol to prevent unspecific protein binding. Therefore, cell adhesion is only mediated via c(-RGDfK-)-covered gold nanodots. (Bottom panels) Mc3t3 osteoblast in contact with a biofunctionalised 80-nm pattern and exhibiting cell protrusions sensing the pattern. Bars: 20 µm (left); 200 nm (right).