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. 2008 Oct 21;3(10):e3464. doi: 10.1371/journal.pone.0003464

Figure 5. RNF10 negatively regulates Schwann cell proliferation.

Figure 5

(A)The time course of cell number was assessed for Schwann cells infected with retrovirus expressing RNF10 siRNA, or control EGFP siRNA by using the MTT assay. Compared to control cells, the RNF10-knockdown Schwann cells exhibited a 40% greater increase. (B) BrdU incorporation was significantly increased (80% greater) in stable RNF10 knockdown cells compared with controls. *p<0.01; Student's t test. Error bars show meanĀ±SD.