Figure 2. Antigen-specific cytokine production by intra-hepatic T-cells in HCV mono-infection and HCV/HIV co-infection.

Figure (a) represents the summary data of the percentage of intra-hepatic CD4⁺ T-cells expressing IFN-γ in response to either HCV or HIV peptide stimulation in all the three studied cohorts, with figure (b) representing the same responses by CD8⁺ T-cells. Figures (c) and (d) represent the percentage of viral-specific, intra-hepatic TNF-α producing CD4⁺ and CD8⁺ T-cells respectively.