Table 1.
Expression of Bax and clinicopathologic characteristics
| Low Bax (%) | High Bax (%) | P valuea | |
|---|---|---|---|
| Gender | |||
| Female | 22 (14) | 23 (48) | <0.0001 |
| Male | 135 (86) | 25 (52) | |
| Age | |||
| ≤63b | 84 (54) | 28 (58) | 0.621 |
| >63 | 73 (46) | 20 (42) | |
| History of smoking | |||
| Yes | 140 (89) | 25 (52) | <0.0001 |
| No | 17 (11) | 23 (48) | |
| Operation | |||
| Lobectomyc | 100 (64) | 39 (81) | 0.023 |
| Pneumonectomy | 57 (36) | 9 (19) | |
| Histologic types | |||
| Squamous | 89 (57) | 7 (15) | <0.0001 |
| Adeno | 54 (34) | 36 (75) | |
| Adenosquamous | 7 (4) | 5 (10) | |
| Othersd | 7 (4) | 0 (0) | |
| Tumor size (cm) | |||
| ≤3.9e | 76 (48) | 29 (60) | 0.187 |
| >3.9 | 81 (52) | 19 (40) | |
| Stagef | |||
| I | 72 (46) | 25 (52) | 0.658 |
| II | 38 (24) | 8 (17) | |
| IIIA | 35 (22) | 10 (21) | |
| IIIB | 12 (8) | 5 (10) | |
| Resection margin | |||
| Negative | 140 (89) | 45 (94) | 0.420 |
| Positive | 17 (11) | 3 (6) | |
| Adjuvant treatment | |||
| No | 89 (57) | 28 (58) | 0.773 |
| Chemotherapy | 7 (4) | 1 (2) | |
| Chemoradiotherapy | 44 (28) | 12 (25) | |
| Radiotherapy | 17 (11) | 7 (15) | |
| Expression of p53 | |||
| Low | 89 (57) | 35 (73) | 0.063 |
| High | 68 (43) | 13 (27) | |
| Expression of galectin-3 | |||
| Low | 88 (56) | 12 (25) | <0.0001 |
| High | 69 (44) | 36 (75) | |
aFisher’s exact test. bMedian age. cIncluding two patients with wedge resection. dIncluding five patients with large cell carcinoma, one with mucoepidermoid carcinoma and one with carcinosarcoma. eMedian longest diameter of primary tumor. fPost-operative pathologic staging.