Table 3.
Characteristics | Number of patients | 5-year disease-free survival (%) | P valueb | 5-year overall survival (%) | P valueb |
---|---|---|---|---|---|
Gender | |||||
Female | 45 | 42 | 0.623 | 55 | 0.327 |
Male | 153 | 36 | 44 | ||
Age | |||||
≤63c | 111 | 38 | 0.875 | 47 | 0.648 |
>63 | 87 | 36 | 46 | ||
History of smoking | |||||
Yes | 158 | 34 | 0.230 | 43 | 0.080 |
No | 40 | 50 | 59 | ||
Operation | |||||
Lobectomyd | 138 | 37 | 0.419 | 49 | 0.063 |
Pneumonectomy | 60 | 37 | 42 | ||
Histologic type | |||||
Squamous | 90 | 40 | 0.687 | 46 | 0.746 |
Non-squamous | 108 | 35 | 46 | ||
Tumor size (cm) | |||||
≤3.9e | 103 | 44 | 0.019 | 52 | 0.026 |
>3.9 | 95 | 29 | 41 | ||
Stagef | |||||
I | 95 | 51 | <0.0001 | 59 | <0.0001 |
II | 45 | 33 | 44 | ||
IIIA | 44 | 20 | 29 | ||
IIIB | 14 | 7 | 21 | ||
Resection margin | |||||
Negative | 181 | 38 | 0.155 | 49 | 0.037 |
Positive | 17 | 24 | 24 | ||
Expression of Bax | |||||
Low | 151 | 35 | 0.381g | 45 | 0.247h |
High | 47 | 45 | 53 | ||
Expression of p53 | |||||
Low | 121 | 38 | 0.579 | 48 | 0.566 |
High | 77 | 36 | 44 | ||
Expression of galectin-3 | |||||
Low | 96 | 34 | 0.237 | 42 | 0.157 |
High | 102 | 40 | 50 |
aExcluding seven patients who died of post-operative complication. bLog-rank test. cMedian age. dIncluding wedge resection. eMedian longest diameter of primary tumor. fPost-operative pathologic staging. gP = 0.103 according to the Wilcoxon test. hP = 0.057 according to the Wilcoxon test.