Table 4.
Prognostic factors | Disease-free survival |
Overall survival |
||||
---|---|---|---|---|---|---|
HR | 95% CI | P valueb | HR | 95% CI | P valueb | |
Operation | ||||||
Lobectomyc | 1.00 | 1.00 | ||||
Pneumonectomy | 1.41 | 0.77–2.62 | 0.269 | 2.63 | 1.45–4.79 | 0.002 |
Tumor size (cm) | ||||||
≤3.9d | 1.00 | 1.00 | ||||
>3.9 | 2.14 | 1.33–3.45 | 0.002 | 1.53 | 0.90–2.61 | 0.118 |
Stagee | ||||||
I | 1.00 | 1.00 | ||||
II | 2.65 | 1.42–4.96 | 0.002 | 1.93 | 0.97–3.85 | 0.062 |
IIIA | 3.76 | 2.09–6.77 | <0.0001 | 2.58 | 1.40–4.76 | 0.002 |
IIIB | 5.23 | 2.08–13.11 | <0.0001 | 3.52 | 1.44–8.62 | 0.006 |
Expression of Bax | ||||||
High | 1.00 | 1.00 | ||||
Low | 1.87 | 1.12–3.14 | 0.017 | 1.79 | 1.04–3.08 | 0.037 |
HR, hazard ratio; CI, confidence interval. aExcluding one patient who died of post-operative complication. bCox proportional-hazards regression model. cIncluding wedge resection. dMedian longest diameter of primary tumor. ePost-operative pathologic staging.