TABLE II.
Examples of G protein-coupled receptors associated wit pathophysiological conditions
| GPCR | Associated pathology | Study |
|---|---|---|
| α-1 adrenergic | Prostate cancer | Canonical |
| BILF1 | Epstein-Barr encoded | [31] |
| CCR6, CCR7, CCR10 | Upregulated by Epstein-Barr virus | [32, 33] |
| CXCR2 | Transforming activity | [34] |
| FPR | Malignant glioma | [35] |
| Grm1 | Melanoma | [36] |
| GPR56 | Glioblastoma multiforme | [37] |
| GPR87 | Non-small cell lung carcinoma | [38] |
| KSHV-GPCR | Kaposi’s sarcoma and primary effusion lymphoma | [39, 40] |
| MC1R | Melanoma | [41, 42] |
| ORF74 | Lymphomas | [43] |
| PSGR | Human prostate neoplasia and prostate tumors | [44] |