. Author manuscript; available in PMC: 2009 Aug 1.

Published in final edited form as: Exp Mol Pathol. 2008 Apr 8;85(1):20–27. doi: 10.1016/j.yexmp.2008.03.004

Table 4.

Interferon-inducible transcripts in ankle tissue from B. burgdorferi -infected mouse ankles

		Interferon-inducible transcript^a
Infected with Mouse strain^c		Cxcl9	Cxcl10	Igtp
BSK^b	(pooled)	64 ± 54	9 ± 7	13.0 ± 7.0
B. burgdorferi	C57BL/6	312 ± 136	46 ± 25	25.1 ± 20.1
	C3H/HeN	475 ± 210	56 ± 11	60.1 ± 21. 1
	TLR2^−/−B6	4079 ± 1388^d	704 ± 232^d	174.0 ± 49.3^d
	TLR2^−/−C3H	4259 ± 2183^d	1321 ± 959^d	225.3 ± 219

RNA was isolated from ankles at 2-week post infection, and RT-PCR was performed. Transcript copy numbers were normalized to 10,000 β-actin.

Transcript copy numbers in mock infected mice (BSK) were similar for all mouse strains, and were pooled to define the basal level for IFN-inducible transcripts.

Each infected group consisted of 5 animals. The BSK group contained 8 mice (2 mice per genotype).

Significantly greater levels were detected in TLR2−/−(B6 and C3H) than in wild type joint tissues (p < 0.05), using One-way ANOVA with Bonferroni as the post test {Wang, 2007 #473}. Copyright 2007 Elsevier, used with permission.