Figure 3. P value and pairwise linkage disequilibrium diagram of the region on chromosome 1q23, area of FCER1A (panel A), and chromosome 5q31, area of RAD50 (panel B).
Pairwise LD, measured as D', was calculated from KORA S3/F3 500 K. Shading represents the magnitude of pairwise LD with a white to red gradient reflecting lower to higher D' values. Gene regions are indicated by colored bars. P value diagram: The x-axis represents the genomic position. The y-axis shows −log10 (P values) of KORA S3/F3 500 K (blue), KORA S4 (black), GINI (yellow), LISA (green), ISAAC (orange), combined replication samples (red).
