Table 2. Agreement between NFI risk groups according to the Bands prediction rule and the adjusted prediction rule.
Variables | Number | NFI event | Univariate | Multivariable (full model) | Multivariable (selected) | |||
HRa | 95% CI | HRa | 95% CI | HRa | 95% CI | |||
All patients | 864 | 115 | ||||||
Sex | ||||||||
Male | 538 | 87 | 1 | 1 | ||||
Female | 326 | 28 | 0.5 | 0.3–0.8 | 0.8 | 0.5–1.2 | ||
Age (years) | ||||||||
<15 | 136 | 11 | 0.6 | 0.3–1.2 | 0.7 | 0.3–1.3 | ||
15–29 | 294 | 39 | 1 | 1 | ||||
30–39 | 161 | 25 | 1.2 | 0.7–2.0 | 1.1 | 0.6–1.8 | ||
≥40 | 273 | 40 | 1.1 | 0.7–1.7 | 0.9 | 0.6–1.3 | ||
WHO leprosy classification | ||||||||
PB | 669 | 29 | 1 | 1 | 1 | |||
MB | 195 | 86 | 13.4 | 8.8–21 | 7.5 | 4.4–13.0 | 8.0 | 5.0–13.0 |
longstanding NFI at diagnosis | ||||||||
No | 792 | 86 | 1 | 1 | ||||
Yes | 72 | 29 | 4.4 | 2.9–6.8 | 1.3 | 0.9–2.1 | ||
Bacterial load b | ||||||||
Negative | 759 | 66 | 1 | 1 | ||||
Positive | 91 | 48 | 8.2 | 5.7–12.0 | 1.0 | 0.6–1.6 | ||
Anti-PGL-I serology | ||||||||
Negative | 605 | 31 | 1 | 1 | 1 | |||
Positive | 259 | 84 | 7.5 | 5.0–11.3 | 2.7 | 1.6–4.5 | 2.9 | 1.8–4.6 |
Table shows number of patients per risk group and (number of patients with NFI event). Totals show number of patients, (number of patients with NFI event) and percentage of NFI events in that particular group.
NFI = nerve function impairment, Bands = Bangladesh acute nerve damage study.