FIG. 1.
Leishmanicidal effects of edelfosine and miltefosine. (A and B) Percentages of PI-positive L. infantum promastigotes after 24 h of treatment with increasing concentrations of edelfosine (A) or miltefosine (B); (C and D) percentages of hypodiploid promastigotes after 24 h of treatment with increasing concentrations of edelfosine (C) or miltefosine (D); (E and F) monoparametric histograms comparing the relative TMRM-derived fluorescence of control and 45 μM edelfosine-treated (E) or 45 μM miltefosine-treated (F) promastigotes. LD50, 50% lethal dose.