Skip to main content
. 2008 Jul 21;52(10):3467–3477. doi: 10.1128/AAC.00439-08

TABLE 5.

Sum of FICs for WR301801 combined with conventional antimalarials

Partner drug ΣFIC (n, range)a
W2
D6
Avg for all dilutions Maximum avg Avg for all dilutions Maximum avg
Mefloquine 1.7 (3, 1.3-2.5) 2.1 (3, 1.5-3.2) 1.8 (3, 1.3-2.1) 2.2 (3, 1.7-2.5)
Chloroquine 1.5 (2, 1.2-1.7) 1.9 (2, 1.7-2.1) 1.5 (2, 1.5-1.5) 2.2 (2, 2.2-2.2)
Azithromycin 1.2 (3, 1.0-1.3) 1.5 (3, 1.2-1.7) 1.3 (3, 1.2-1.4) 1.7 (3, 1.5-1.9)
Artemisinin 1.7 (3, 1.7-1.8) 2.1 (3, 2.0-2.1) 1.8 (3, 1.7-2.0) 2.1 (3, 1.9-2.3)
a

FICs of <0.5, 1, and >2 are normally considered to be synergistic, additive, and synergistic, respectively. n, number of experiments.