TABLE 4.
In vitro susceptibilities of the molds to various antifungal agents determined by the EUCAST methodology
| Species | No. of isolates | Range and GM MIC or MEC (μg/ml)
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMB
|
l-AMB
|
CPF
|
ITC
|
VRC
|
POS
|
||||||||
| MIC range | GM MIC | MIC range | GM MIC | MEC range | GM MIC | MIC range | GM MIC | MIC range | GM MIC | MIC range | GM MIC | ||
| Aspergillus species | |||||||||||||
| Aspergillus fumigatus | 29 | 0.5-2 | 0.69 | 0.5-2 | 0.31 | 0.25-1 | 0.45 | 0.5-1 | 0.46 | 0.25-1 | 0.36 | 0.5-1 | 0.37 |
| Aspergillus terreus | 34 | 2-4 | 2.82 | 2-4 | 2.84 | 0.125-1 | 0.19 | 0.5-1 | 0.58 | 0.25-1 | 0.29 | 0.125-0.5 | 0.19 |
| Aspergillus flavus | 21 | 1-4 | 1.51 | 1-4 | 1.38 | 0.25-1 | 0.28 | 0.5-2 | 0.59 | 0.5-2 | 0.41 | 0.125-0.5 | 0.21 |
| Aspergillus niger | 13 | 0.5-4 | 1.00 | 1-2 | 1.23 | 0.25-1 | 0.36 | 2-4 | 0.98 | 0.5-2 | 0.33 | 0.25-0.5 | 0.26 |
| Zygomycetes | |||||||||||||
| Rhizomucor species | 17 | 0.25-1 | 0.58 | 0.3-0.125 | 0.39 | >8 | >8 | >8 | 1-4 | 2.23 | |||
| Absidia corymbifera | 4 | 1-1 | 1.00 | 0.125-1 | 0.43 | >8 | 1-2 | 2.50 | >8 | 0.5-1 | 0.29 | ||
| Absidia species | 17 | 0.5-1 | 0.80 | 0.5-2 | 0.72 | >8 | 4->8 | >8 | 0.5-2 | 0.33 | |||
| Rhizopus microsporus var. oligosporus | 3 | 1-1 | 1.00 | 0.03-0.25 | 0.13 | >8 | 8->8 | >8 | 4-8 | 5.33 | |||
| Rhizopus oryzae | 6 | 2-4 | 3.00 | 1-4 | 2.00 | >8 | 4 | 4.00 | >8 | 1-2 | 1.89 | ||
| Rhizopus species | 12 | 1-4 | 2.08 | 1-4 | 2.50 | >8 | >8 | >8 | 2-4 | 0.78 | |||
| Mucor hiemalis | 3 | 0.5-1 | 0.86 | 0.03-0.5 | 0.21 | >8 | 8->8 | >8 | 1-2 | 1.33 | |||
| Mucor species | 11 | 0.5-1 | 0.73 | 0.03-0.5 | 0.38 | >8 | 4-8 | 4.36 | >8 | 2-4 | 0.72 | ||
| Cunninghamella species | 4 | 0.5-4 | 2.25 | 0.5-4 | 1.47 | >8 | 1-4 | 1.75 | >8 | >8 | 1-2 | 2.00 | |
| Others | |||||||||||||
| Scedosporium prolificans | 2 | >8 | >8 | >8 | >8 | >8 | >8 | ||||||
| Scedosporium apiospermum | 3 | 2-4 | 2.66 | 1-2 | 1.33 | >8 | 2-4 | 2.66 | 2->8 | 0.5-2 | 1.00 | ||
| Penicillium marneffi | 2 | 1-2 | 1.5 | 0.03-0.25 | 0.14 | >8 | 0.01-0.5 | 0.25 | >8 | 0.06 | 0.06 | ||
| Penicillium species | 2 | 0.5-1 | 0.75 | 0.5-1 | 0.75 | >8 | 0.5-8 | 4.25 | 2->8 | 0.5 | 0.05 | ||
| Fusarium solani | 2 | 4 | 1.00 | 4-8 | 6.00 | >8 | 4-8 | 6.00 | >8 | 1 | 1 | ||
| Fusarium oxysporum | 2 | 1-4 | 2.5 | 0.03-0.5 | 0.10 | >8 | 1-8 | 4.50 | 4->8 | 0.125 | 0.12 | ||
| Sporothrix schenckii | 2 | 1-4 | 2.5 | 1-2 | 1.50 | >8 | 0.125 | 0.12 | >8 | 0.25 | 0.25 | ||
| Curvularia lunata | 2 | 0.5-1 | 0.75 | 0.125-0.5 | 0.31 | >8 | 0.03 | 0.03 | >8 | 0.25 | 0.25 | ||
| Bipolaris australiensis | 2 | 1 | 1.00 | 0.01-0.06 | 0.03 | >8 | 0.125 | 0.12 | >8 | 0.125 | 0.12 | ||
| Rhinocladiella aquaspersa | 2 | 1 | 1.00 | 0.5-1 | 0.75 | >8 | 0.125 | 0.12 | >8 | 0.06 | 0.06 | ||