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. 2008 Jul 14;52(10):3497–3503. doi: 10.1128/AAC.00478-08

FIG. 5.

FIG. 5.

(A) Relationship between micafungin (○) and anidulafungin (▴) free-drug 24-h AUC/MIC and efficacy against four C. albicans strains. Each symbol represents the mean CFU/kidneys from three mice. Efficacy on the y axis is expressed as the change in CFU/kidneys compared to the burden of organisms compared to the start of therapy. The dashed horizontal line represents the burden of organisms in thighs at the start of therapy. (B) Relationship between micafungin (○) and anidulafungin (▴) free-drug 24-h AUC/MIC and efficacy against ten C. glabrata strains. Each symbol represents the mean CFU/kidneys from three mice. Efficacy on the y axis is expressed as the change in CFU/kidneys compared to the burden of organisms compared to the start of therapy. The dashed horizontal line represents the burden of organisms in thighs at the start of therapy.