TABLE 4.
Efficacy of killed KBNP-C4152R2L oil emulsion vaccine against a different genotype (III) virus, KJW
| Group | Vaccine titer (EID50) | Test virus | HI titer (log2) at DPI:
|
Survival ratea | |
|---|---|---|---|---|---|
| 7 | 21 | ||||
| Control | 0 | La Sota | 0 | 0 | 1/10 (10) |
| KBNP-C4152R2L | 0 | 0 | |||
| KBNP-C4152R2L | 109.1 | La Sota | NTb | 7.1 ± 1.1 | 15/15 (100) |
| KBNP-C4152R2L | 0.2 ± 0.4 | 7.5 ± 1.2 | |||
| La Sota | 109.2 | La Sota | 0.2 ± 0.6 | 6.9 ± 1.5 | 8/9 (89) |
| KBNP-C4152R2L | 0 | 4.6 ± 1.5 | |||
a
Survival rate after challenge with KJW (2 × 105 TCID50/chicken on DPI 22 via the intranasal route), shown as number surviving/total number challenged (percent).
b
NT, not tested.