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Digital image analysis of nucleoids from E. colia
| Dose (μg/ml) | n | Surface area (mean ± SD) | Relative increase in surface area | P |
|---|---|---|---|---|
| 0 | 150 | 7,411.9 ± 2,173.8 | ||
| 0.012 | 145 | 29,198.8 ± 12,747.9 | 3.9 | <0.0001 |
| 5.0 | 146 | 85,156.8 ± 19,301.1 | 11.5 | <0.0001 |
Nucleoids were treated with ciprofloxacin for 40 min in LB broth and processed with the Micro-Halomax kit. n, number of nucleoids examined; P, significance level obtained with Mann-Whitney U test; surface area is shown in number of pixels.
