Table 3 Antiretroviral therapy use, adherence, immunological and virological markers by time since HAART initiation stratified by HIV RNA ⩾ 300 or <300 copies/ml at the fifth year after HAART initiation.
Years from HAART initiation | HIV RNA <300 copies/ml at fifth year after HAART (n = 517) | HIV RNA ⩾300 copies/ml at fifth year after HAART (n = 423) | ||||||
---|---|---|---|---|---|---|---|---|
⩾−1 and <0 | ⩾0 and <1 | ⩾1 and <3 | ⩾3 and <5 | ⩾−1 and <0 | ⩾0 and <1 | ⩾1 and <3 | ⩾3 and <5 | |
Number of person visits | 913 | 887 | 1660 | 1753 | 757 | 705 | 1307 | 1332 |
NRTI, % | ||||||||
= 0 | 31 | 0 | 0 | 0 | 26 | 0 | 0 | 0 |
= 1 | 17 | 2 | 9 | 9 | 22 | 4 | 12 | 10 |
⩾2 | 52 | 98 | 91 | 91 | 52 | 96 | 88 | 90 |
PI, % | ||||||||
= 0 | 95 | 12 | 16 | 41 | 93 | 9 | 16 | 31 |
= 1 | 4 | 76 | 68 | 43 | 7 | 75 | 61 | 45 |
⩾2 | 1 | 12 | 16 | 16 | <1 | 16 | 23 | 24 |
NNRTI, % | ||||||||
= 0 | >99 | 83 | 68 | 54 | 99 | 85 | 65 | 54 |
= 1 | <1 | 17 | 32 | 45 | 1 | 15 | 34 | 44 |
⩾2 | 0 | 0 | <1 | 1 | 0 | 0 | 1 | 2 |
Adherence, % | n = 125 | n = 1207 | n = 1740 | n = 77 | n = 902 | n = 1317 | ||
100 | NA | 39 | 42 | 40 | NA | 36 | 36 | 34 |
95–99 | NA | 40 | 45 | 47 | NA | 38 | 39 | 41 |
75–94 | NA | 15 | 9 | 12 | NA | 22 | 18 | 17 |
<75 | NA | 6 | 4 | 1 | NA | 4 | 7 | 8 |
CD4 (cells/mm3) | ||||||||
Median | 313 | 386 | 470 | 528 | 249 | 318 | 352 | 339 |
IQR | 178–461 | 246–550 | 306–656 | 351–728 | 150–400 | 199–461 | 213–532 | 196–541 |
HIV RNA (copies/ml) | ||||||||
Median | 13244 | 115 | <80 | <80 | 28000 | 2554 | 3500 | 4365 |
IQR | 3744–64000 | <80–1551 | <50–505 | <50–80 | 5500–110000 | 200–19000 | 320–23000 | 690–23195 |