TABLE 4.
Susceptibility of M. chelonae, M. abscessus, and M. bolletii isolates to clarithromycin
| Species (n) | Strain | MIC (μg/ml) | Susceptibilitya | Mutation |
|---|---|---|---|---|
| M. abscessus (10) | ATCC19977T | 2 | S | Nb |
| RGM81 | 0.5 | S | N | |
| RGM109 | 8 | R | N | |
| RGM130 | 4 | I | N | |
| RGM157 | 0.5 | S | N | |
| RGM174 | 4 | I | N | |
| RGM185 | 64 | R | N | |
| RGM220 | 0.25 | S | N | |
| RGM239 | 64 | R | N | |
| RGM240 | 64 | R | N | |
| M. massiliense | CIP 108297T | 0.5 | S | N |
| (10) | RGM65 | 0.125 | S | N |
| RGM70 | 0.25 | S | N | |
| RGM145 | >256 | R | A2058G | |
| RGM234 | 0.5 | S | N | |
| RGM247 | >256 | R | A2059G | |
| RGM250 | 0.25 | S | N | |
| RGM264 | >256 | R | A2058G | |
| RGM270 | 0.25 | S | N | |
| RGM279 | 0.5 | S | N | |
| M. bolletii (3) | CIP 108541T | 8 | R | N |
| Asan30754 | 8 | R | N | |
| RGM231 | 16 | R | N |
a
S, susceptible; R, resistant; I, intermediate.
b
N, none.