TABLE 3.
Sensitivities and specificities of the DRW and Determine HBsAg rapid tests with selected low-titer HBsAg EIA-positive or HBsAg EIA-negative blood donor samples at the BRCBC
| HBsAg panel | Sensitivitya
|
Specificityb
|
||
|---|---|---|---|---|
| DRW | Determine | DRW | Determine | |
| Mixed-titer panel (n = 126) | 126/126 (100 [100-100]) | 110/126 (87.3 [81.5-93.1]) | ||
| EIA-positive QC panel (n = 20) | 20/20 (100 [100-100]) | 3/20 (15.0 [0-30.6]) | ||
| EIA-negative donor samples (n = 498) | 492/498 (98.8 [97.8-99.8]) | 498/498 (100 [100-100]) | ||
a
Expressed as the number of samples positive by the indicated test/number positive by EIA (percentage [95% CI]). The differences in sensitivity between the DRW and Determine tests were significant at P values (determined by McNemar's test) of <0.0001 for both the HBsAg mixed-titer panel and the HBsAg EIA-positive QC panel.
b
Expressed as the number of samples negative by the indicated test/number negative by EIA (percentage [95% CI]). The P value (determined by McNemar's test) for the difference in specificity between the DRW and Determine tests was 0.0313.