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. 2008 Aug 13;46(10):3232–3236. doi: 10.1128/JCM.00908-08

TABLE 3.

Summary of minimal inhibitory drug dilutions and AEs of topical ocular drugs

Drug Minimal inhibitory dilution AE
Proparacaine (anesthetic) 1/1 100.1
Prednisolone (steroid) 1/1 91.2
Bromfenac (nonsteroidal) 1/1 97.4
Nepafenac (nonsteroidal) 1/10 95.0
Gatifloxacin (antibiotic) 1/10 92.6
Moxifloxacin (antibiotic) 1/10 92.0
Tobramycin (antibiotic) 1/1 102.9
Cefazolin (antibiotic) 1/10 91.6
Amphotericin B (antifungal) 1/1 108.7
Trifluridine (antiviral) 1/40a 94.6
Propamidine (antiacanthamoebic) 1/10 85.7
Polyhexamethylene biguanide (antiacanthamoebic) 1/640b 72.7
Chlorhexidine (antiacanthamoebic) 1/10 77.0
Corneal tissue 1/1 86.9
a

Trifluridine inhibition was removed completely after DNA extraction (1/1).

b

Polyhexamethylene biguanide inhibition was still present after DNA extraction (the minimal inhibitory dilution improved onefold to 1/320).