Figure 4.

Human PON1 expression. (A) PON1 tissue expression. RT-PCR was performed on placenta (Pl), muscle (Mus), stomach (St), kidney (K), intestine (In), liver (L), pancreas (Panc) and lung (Lu). B, blank; M, marker. Upper panel shows PON1 expression, lower panel shows GAPDH control expression. (B) Monoallelic expression of human PON1 in the liver and pancreas. Biallelic sequencing results of a human PON1 polymorphism from foetal samples are shown in the top panels. cDNA sequencing of PON1 in the liver (left panel) and pancreas (right panel) showing monoallelic expression of the polymorphism (bottom panels).