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. 1999 Nov;10(11):3705–3715. doi: 10.1091/mbc.10.11.3705

Figure 6.

Figure 6

Domains of Res1 and Res2 required for periodic regulation of cdc18+ transcription. Schematics describing the Res1–Res2 hybrids used in this study are shown in A. The small striped boxes represent the ankyrin repeats, and the solid box indicates the DNA-binding domain. Res2 sequences are represented by open boxes; Res1 sequences are shaded gray. Δres2 cells (A) or Δres1 cells (B) were transformed with the appropriate plasmid. Exponentially growing cells were treated with hydroxyurea (11 mM), and incubation was continued for 3 and 4.5 h. RNA was prepared from samples and subjected to Northern analysis with cdc18+ and his3+. A comparison with wild-type cells is shown above in a.