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. Author manuscript; available in PMC: 2008 Oct 13.
Published in final edited form as: Biochemistry. 2006 Jan 10;45(1):11–19. doi: 10.1021/bi051502y

Figure 8.

Figure 8

Mechanism for activation of the acyl adenylate intermediate. The water molecule is also within hydrogen bonding distances of the amide groups of Gly37 and Gly40 and the carbonyl group of Cys125.