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. Author manuscript; available in PMC: 2008 Oct 13.
Published in final edited form as: J Am Chem Soc. 2007 Aug 2;129(33):10220–10228. doi: 10.1021/ja072185g

Figure 6.

Figure 6

DNA polymerase stop assay using RET-Pol2 as the template with the addition of increasing concentrations of TMPyP4 (0, 1, 2 and 5 µM) and telomestatin (0, 0.1, 0.5 and 2 µM) in 10 mM KCl/NaCl. Sequencing reactions for G and C are shown on the left side of the gel. (B) CD spectra of RET31 with increasing concentrations of TMPyP4 from 1-mole equivalence to 4-mole equivalence in Tris-HCl buffer (20 mM, pH 7.6), 10 mM KCl. (C) CD spectra of RET31 with increasing concentrations of telomestatin from 1-mole equivalence to 4-mole equivalence in Tris-HCl buffer (20 mM, pH 7.6), 10 mM KCl.