Table 3.
Multiple logistic regression analysis of dilated cardiomyopathy patients clinical characteristics and genotype to implantable cardioverter-defibrillator (history of ventricular tachycardia or ventricular fibrillation) prior to study entry (χ2 = 25.098; df = 10; P = 0.005)
| Variable | ICD (history of VT or VF) |
||
|---|---|---|---|
| OR | 95% CI | P-value | |
| Genetic variant | |||
| Ser96Ala (T→G) | |||
| T/G compared with T/T | 6.166 | 0.714–53.228 | 0.098 |
| G/G compared with T/T | 18.213 | 1.974–168.073 | 0.010 |
| Clinical characteristics | |||
| Age | 1.061 | 1.014–1.110 | 0.010 |
| Sex | 1.504 | 0.422–5.359 | 0.529 |
| Familial DCM | 0.394 | 0.133–1.166 | 0.093 |
| NYHA | |||
| Class I compare with III | 1.946 | 0.335–11.299 | 0.458 |
| Class II compare with III | 1.530 | 0.298–7.863 | 0.610 |
| AF | 0.630 | 0.164–2.421 | 0.501 |
| LBBB | 0.439 | 0.136–1.415 | 0.168 |
| LVEF | 0.963 | 0.890–1.041 | 0.338 |
ICD, implantable cardioverter-defibrillator; NYHA, New York Heart Association; AF, atrial fibrillation; LBBB, left bundle branch block; LVEF, left ventricular ejection fraction; OR, odds ratio; CI, confidence interval; df, degrees of freedom; with bold statistical significant associations.