Table 2. Correlations for individual cytokine responses to various mycobacterial antigens and PHA in BCG vaccinated infants.
IFN-γ PHA | IFN-γ PPD | IFN-γ Ag85 | IFN-γ STCF | IFN-γ KMTB | |||||||||||
Na | ρb | p valuec | N | ρb | p value | N | ρb | p value | N | ρb | p value | N | ρb | p value | |
IFN-γ PHA | - | - | - | 188 | 0.176 | 0.0156 | 171 | 0.466 | 1.37×10−10 | 166 | 0.0629 | 0.421 | 188 | 0.089 | 0.224 |
IFN-γ PPD | - | - | - | 200 | 0.540 | 1.5×10−16 | 207 | 0.675 | 7.38×10−29 | 229 | 0.543 | 5.79×10−19 | |||
IFN-γ Ag85 | - | - | - | 186 | 0.503 | 2.39×10−13 | 200 | 0.340 | 8.22×10−7 | ||||||
IFN-γ STCF | - | - | - | 209 | 0.615 | 3.57×10−23 | |||||||||
IFN-γ KMTB | - | - | - |
Number of infants for whom both cytokine data were available for correlation analysis.
Spearman rank-order correlation coefficient.
ρ values>0.3 with corresponding p values≤0.05 are shown in bold.
IFN-γ: interferon-gamma; IL-13: interleukin-13; IL-5: interleukin-5; PHA: phytohaemagglutinin; PPD: purified protein derivative; Ag85: antigen 85; STCF: short term culture filtrate; KMTB: killed Mycobacterium tuberculosis.