Table 3. Correlations between different cytokines responses to individual mycobacterial antigens.
Antigen | cytokine | IL-13 | IL-5 | ||||
Na | ρb | p value | Na | ρb | p value | ||
PHA | IFN-γ | 126 | 0.411 | 1.76×10−6 | 40 | 0.022 | 0.892 |
IL-13 | - | - | - | 28 | 0.334 | 0.082 | |
PPD | IFN-γ | 153 | 0.226 | 0.005 | 88 | −0.150 | 0.164 |
IL-13 | - | - | - | 60 | 0.223 | 0.0865 | |
Ag85 | IFN-γ | 59 | 0.141 | 0.286 | 35 | −0.368 | 0.0295 |
IL-13 | - | - | - | 12 | −0.654 | 0.0211 | |
STCF | IFN-γ | 109 | 0.285 | 0.0027 | 50 | −0.0893 | 0.537 |
IL-13 | - | - | - | 30 | −0.129 | 0.496 | |
KMTB | IFN-γ | 138 | 0.398 | 1.33×10−6 | 76 | 0.071 | 0.542 |
IL-13 | - | - | - | 45 | 0.14 | 0.361 |
Number of infants for whom both cytokine data were available for correlation analysis.
Spearman rank-order correlation coefficient.
ρ values>0.3 with corresponding p values≤0.05 are shown in bold.
IFN-γ: interferon-gamma; IL-13: interleukin-13; IL-5: interleukin-5; PHA: phytohaemagglutinin; PPD: purified protein derivative; Ag85: antigen 85; STCF: short term culture filtrate; KMTB: killed Mycobacterium tuberculosis.