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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Clin Immunol. 2008 Aug 16;129(1):31–35. doi: 10.1016/j.clim.2008.07.011

Table I.

Association of mtDNA markers with multiple sclerosis (MS) and systemic lupus erythematosus SLE. All p<0.05 are indicated. After correction for multiple testing, significant associations are observed for the mtDNA nt9055 variant of the ATP6 gene (in haplogroup K) in both MS and SLE, and for the nt4719 variant of the ND2 gene (in haplogroup T) in MS.

Gene ND2 ATP6 CYTB
Marker Mt4917 mt9055 mt14798
MS-control χ2 7.56 34.7 4.76
p 0.006 <0.0001 0.029
Associated variant G(A/G) A(G/A) C(T/C)
Freq. in controls/MS 0.876/0.928 0.024/0.133 0.151/0.205
SLE-control χ2 11.8 7.45 0.31
p 0.033 0.006 0.576
Associated * G(A/G) A(G/A) C(T/C)
Freq. in controls/SLE * 0.876/0.970 0.025/0.089 0.849/0.872