Table 2.
Comparison Between Mesenchymal Stem Cells (MSCs) and Nucleus Pulposus (NP) Cells
Chemical Factor | Variable | MSCs (Rat) | NP Cells (Human*/Bovine#) |
---|---|---|---|
Glucose | Gene expression of matrix proteins | ↑ (5.56 mmol/L) | N.A. |
Proliferation | ⇆ (5.56 mmol/L) | N.A. | |
Viability | N.A. | ⇆ (5 mmol/L#) [4] | |
Osmolarity | Gene expression | ↓ (485 mOsm) | ↑ 500 mOsm*/# [50] |
Proliferation | ↓ (485 mOsm) | N.A. | |
Viability | N.A. | N.A. | |
pH | Gene expression | ↓ (pH 6.8) | N.A. |
Proliferation | ↓ (pH 6.8) | N.A. | |
Viability | N.A. | ↓ (pH 6.2; first signs at pH 6.7) [4] |