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. 2008 Sep 16;99(7):1056–1063. doi: 10.1038/sj.bjc.6604634

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Copyright © 2008 Cancer Research UK

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Tumour protein expression levels of EGFR, Akt, NF-κB, b-Raf, ERK and MEK after treatment with EGCG and tamoxifen. Mice were treated with vehicle (5 ml kg⁻¹), EGCG (25 mg kg⁻¹, i.p.), tamoxifen (75 μg kg⁻¹, p.o.), or EGCG+tamoxifen for 70 days. (A) Representative western blots of the various proteins from each individual mouse. (B) The results of scanning densitometry of western blots. For clarity, densitometry is shown only for proteins that were modulated by drug treatment. Bars represent the mean±s.e.m. from 10 mice per group. ^*Significantly different from vehicle control (P<0.05). ^**Significantly different from vehicle and EGCG (P<0.01). ^***Significantly different from all other treatments (P<0001).