Table 5. Five-year OS and RFS for stage 1 and stage 2 patients without MYCNA.

	Stage 1							Stage 2
Characteristics	Cases	No. of deaths	OS	P-value	No. of events	RFS	P-value	Cases	No. of deaths	OS	P-value	No. of events	RFS	P-value
	288	3	98.9		16	94.3		123	9	93.2		22	82.8
Gender							<0.05				0.79			0.16
Male	167				13	92		61	4	93.2		8	88.5
Female	121				3	97.5		62	5	93.4		14	77.4
Age (years)							0.91				0.07			0.90
0–17	185				10	94.5		76	3	96.0		14	81.5
⩾18	103				6	94.1		47	6	88.7		8	85.0
Primary site							0.79				0.45			0.076
Neck	14				1	92.9		7	1	100		2	71.4
Thorax	65				3	95.4		43	2	95.3		4	90.7
Abdomen	197				12	93.7		61	6	89.6		11	81.8
Pelvis	12				0	100		12	0	100		5	66.7
LN infiltration											0.50			0.79
Absent	0							53	3	94.3		9	83.0
Present	0							70	6	92.4		13	82.7
Serum LDH							0.061				<0.0001			0.050
Normal	161				7	95.6		95	5	95.7		15	85.2
Increased	12				2	83.3		8	4	50		3	62.5
Missing	115							20
Urine VMA							0.44				0.20			0.87
Normal	118				5	95.8		32	3	90.4		6	84.4
Increased	57				4	92.8		40	1	97.5		7	82.5
Missing	113							51
Urine HVA							0.28				0.31			0.39
Normal	108				4	96.3		36	3	91.4		8	80.6
Increased	52				4	92.1		35	1	97.1		5	85.7
Missing	128							52
Histopathologic category							0.78				<0.0004			<0.0035
Favourable	191				10	94.7		83	3	96.4		12	85.5
Unfavourable	25				1	96		21	6	75.9		9	61.2
Missing	72							19
DNA index							0.40				0.31			0.40
Aneuploid	90				7	92.2		47	3	93.6		8	83
Di-tetraploid	50				4	91.5		29	4	85.9		7	79.3
Missing	148							47

HVA=homovanillic acid; LDH=lactate dehydrogenase; LN=lymph node; OS=overall survival; RFS=relapse-free survival; VMA=vanillylmandelic acid.