Figure 10.

Performance of kf-1^−/− mice in the elevated plus maze test. At the start of the test, mice were placed individually in the crossing center from open and closed arms. Data are given as mean (±SEM). (A) Number of entries into the center crossing between open and closed arms. (B) Total distance (centimeters) traveled. (C) % Number of entries into open arms. (D) % Time spent on open arms. Note that the closed arms were enclosed at both sides by transparent walls, and therefore mice could recognize visibly their position on heights even on the closed arms. **p < 0.005; ***p < 0.0005 (see Section ‘Elevated plus maze test’). WT and KO stand for kf-1^+/+ and kf-1^−/− mice, respectively.