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. Author manuscript; available in PMC: 2009 Aug 2.
Published in final edited form as: DNA Repair (Amst). 2008 May 20;7(8):1213–1220. doi: 10.1016/j.dnarep.2008.03.025

Figure 3. Increased HPRT mutant frequency in NEIL1-deficient cells.

Figure 3

V79 (upper panel) and A549 cells (lower panel) were nontreated (NT) or treated with sense or antisense oligonucleotides to NEIL1, then treated with (+) or without (−) glucose oxidase (GO) for 1h to induce oxidative stress. NT, non-treated; S, sense oligonucleotide, AS, antisense oligonucleotide. The HPRT mutants were scored in 6-TG-containing HAT medium. The bar graphs represent the means ± standard error from 4 independent experiments.